La Roche-Posay Effaclar Adapalene Gel 0.1% Advanced Acne Treatment in 45gLa Roche Posay Effaclar Adapalene Gel 0. 1% 45g Important: Adapalene 0. 1% is a pharmaceutical grade retinoid. Use under the supervision of a dermatologist or qualified healthcare professional for best results and skin safety. La Roche Posay Effaclar Adapalene Gel 0. 1% is a clinically proven retinoid acne treatment formulated for acne prone skin. Adapalene a third generation retinoid works at the cellular level to increase skin cell turnover, prevent